Dextromethorphan Hydrobromide and Quinidine Sulfate and PosiFlush flush

• Generic Name: dextromethorphan / quinidine
• Dosage Forms: n.a.
• Other Brand Names: Nuedexta

The fixed combination of dextromethorphan hydrobromide and quinidine sulfate (dextromethorphan/quinidine; Nuedexta) is used in the treatment of PBA.

PBA occurs secondary to various otherwise unrelated neurologic conditions (e.g., amyotrophic lateral sclerosis [ALS], multiple sclerosis [MS], dementia of the Alzheimer's type [Alzheimer's disease] or other dementia, parkinsonian syndrome, stroke, traumatic brain injury) and is characterized by involuntary, sudden, uncontrollable, and frequent episodes of laughing and/or crying. PBA episodes typically occur out of proportion or incongruent to the underlying emotional state.

Studies supporting efficacy in PBA were conducted in patients with underlying ALS or MS.

Safety and efficacy in the treatment of other common types of emotional lability (e.g., those occurring in patients with Alzheimer's disease and other dementias) not established.

• Generic Name: heparin flush
• Dosage Forms: n.a.
• Other Brand Names: Heparin Lock flush, Monoject Prefill Advanced, PosiFlush

PosiFlush is an anticoagulant (blood thinner) that prevents the formation of blood clots.

PosiFlush is used to flush (clean out) an intravenous (IV) catheter, which helps prevent blockage in the tube after you have received an IV infusion.

PosiFlush should not be used to treat or prevent blood clots in the body. A separate this medicine product is available to use for this purpose.

PosiFlush may also be used for purposes not listed in this medication guide.