Dextromethorphan Hydrobromide and Quinidine Sulfate and Reclipsen

• Generic Name: dextromethorphan / quinidine
• Dosage Forms: n.a.
• Other Brand Names: Nuedexta

The fixed combination of dextromethorphan hydrobromide and quinidine sulfate (dextromethorphan/quinidine; Nuedexta) is used in the treatment of PBA.

PBA occurs secondary to various otherwise unrelated neurologic conditions (e.g., amyotrophic lateral sclerosis [ALS], multiple sclerosis [MS], dementia of the Alzheimer's type [Alzheimer's disease] or other dementia, parkinsonian syndrome, stroke, traumatic brain injury) and is characterized by involuntary, sudden, uncontrollable, and frequent episodes of laughing and/or crying. PBA episodes typically occur out of proportion or incongruent to the underlying emotional state.

Studies supporting efficacy in PBA were conducted in patients with underlying ALS or MS.

Safety and efficacy in the treatment of other common types of emotional lability (e.g., those occurring in patients with Alzheimer's disease and other dementias) not established.

• Generic Name: desogestrel / ethinyl estradiol
• Dosage Forms: tablets
• Other Brand Names: Azurette, Cyclessa, Desogen, Isibloom, Kariva, Mircette, Reclipsen, Apri, Bekyree, Caziant, Ortho-Cept, Solia, Cesia, Cyred

Reclipsen is a combination birth control pill containing female hormones that prevent ovulation (the release of an egg from an ovary). Reclipsen also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Reclipsen is used to prevent pregnancy. There are many brands of this medicine available. Not all brands are listed on this leaflet.

Reclipsen may also be used for purposes not listed in this medication guide.