Dextromethorphan Hydrobromide and Quinidine Sulfate and Sulfacetamide

• Generic Name: dextromethorphan / quinidine
• Dosage Forms: n.a.
• Other Brand Names: Nuedexta

The fixed combination of dextromethorphan hydrobromide and quinidine sulfate (dextromethorphan/quinidine; Nuedexta) is used in the treatment of PBA.

PBA occurs secondary to various otherwise unrelated neurologic conditions (e.g., amyotrophic lateral sclerosis [ALS], multiple sclerosis [MS], dementia of the Alzheimer's type [Alzheimer's disease] or other dementia, parkinsonian syndrome, stroke, traumatic brain injury) and is characterized by involuntary, sudden, uncontrollable, and frequent episodes of laughing and/or crying. PBA episodes typically occur out of proportion or incongruent to the underlying emotional state.

Studies supporting efficacy in PBA were conducted in patients with underlying ALS or MS.

Safety and efficacy in the treatment of other common types of emotional lability (e.g., those occurring in patients with Alzheimer's disease and other dementias) not established.

• Generic Name: sulfacetamide sodium ophthalmic
• Dosage Forms: ophthalmic ointment
• Other Brand Names: Bleph-10, Cetamide, Isopto Cetamide, Sodium Sulamyd, Sulf-10, AK-Sulf, Ocusulf-10, Sulfac 10%, Sulfacet Sodium, Ocu-Sul 10, Ocu-Sul 15, Ocu-Sul 30

Sulfacetamide is an antibiotic.

Sulfacetamide ophthalmic (for use in the eyes) is used to treat bacterial infections of the eyes.

sulfacetamide ophthalmic will not treat a viral or fungal infection. Sulfacetamide ophthalmic is for use only in treating eye infections caused by bacteria.

Sulfacetamide ophthalmic may also be used for purposes not listed in this medication guide.