Dextromethorphan, phenylephrine, and pyrilamine and Lorbrena

• Generic Name: dextromethorphan / phenylephrine / pyrilamine
• Dosage Forms: oral suspension
• Other Brand Names: Codal-DM Syrup, Codimal DM, Codituss DM, Poly Hist DM, Viravan-DM, V-Tan DM, Zotex-12, Deconsal DM Tannate, Aldex DM, Viratan-DM, Triplex DM, MyHist-DM, Tannate V DM, Reme Hist DM, Pryil DM, Pyril DM

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan, phenylephrine, and pyrilamine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

dextromethorphan, phenylephrine, and pyrilamine will not treat a cough that is caused by smoking, asthma, or emphysema.

Dextromethorphan, phenylephrine, and pyrilamine may also be used for purposes not listed in this medication guide.

• Generic Name: lorlatinib
• Dosage Forms: tablet, film coated
• Other Brand Names: Lorbrena

Lorbrena (lorlatinib) is prescription medicine used to treat a certain type of non-small cell lung cancer that has spread to other parts of the body.

Lorbrena is used only if your cancer has a specific genetic marker (an abnormal "ALK" gene). Your doctor will test you for this gene.

Lorbrena is given after other cancer treatments did not work or have stopped working.

Lorbrena was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to this medicine, but further studies are needed.