Dextrose 50% Injection and Eliglustat Tartrate

• Generic Name: glucose
• Dosage Forms: injection, solution
• Other Brand Names: BD Glucose, Dex4, Insta-Glucose, Relion Grape, TRUEplus, Trutol Fruit Punch, Dextrose, Rematex, Ziks Arthritis Pain Relief

Dextrose is a form of glucose (sugar). Dextrose 5% in water is injected into a vein through an IV to replace lost fluids and provide carbohydrates to the body.

Dextrose 5% in water is used to treat low blood sugar (hypoglycemia), insulin shock, or dehydration (fluid loss). Dextrose 5% in water is also given for nutritional support to patients who are unable to eat because of illness, injury, or other medical condition.

Dextrose 5% in water is sometimes used as a diluent (liquid) for preparing injectable medication in an IV bag. A diluent provides a large amount of fluid in which to dilute a small amount of medicine. The diluent helps carry the medicine into your bloodstream through the IV. This helps your caregivers inject the medicine slowly and more safely into your body.

Dextrose 5% in water may also be used for purposes not listed in this medication guide.

• Generic Name: eliglustat
• Dosage Forms: n.a.
• Other Brand Names: Cerdelga

Long-term treatment of nonneuronopathic (type 1) Gaucher disease in patients who are extensive, intermediate, or poor metabolizers of CYP2D6.

Patient selection and dosing based on CYP2D6 metabolizer status; determine patient's CYP2D6 genotype with an FDA-cleared test prior to initiating therapy.

Ultrarapid CYP2D6 metabolizers may not achieve adequate plasma concentrations to achieve a therapeutic effect. A specific dosage cannot be recommended for patients whose CYP2D6 genotype cannot be determined (indeterminate metabolizers).

Designated an orphan drug by FDA for treatment of type 1 Gaucher disease.