Di-Gel Liquid and Methadone Tablets for Oral Suspension
Determining the interaction of Di-Gel Liquid and Methadone Tablets for Oral Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Methadone can cause an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. The risk is increased if you have low blood levels of magnesium or potassium, which can occur with bowel cleansing preparations or excessive use of medications that have a laxative effect. Do not exceed the dose and duration of use of magnesium hydroxide recommended on the product label or prescribed by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications. In addition, you should let your doctor know if you experience signs and symptoms of low magnesium or potassium blood level such as weakness, tiredness, drowsiness, dizziness, confusion, tingling, numbness, muscle pain, cramps, nausea, or vomiting. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in patients treated with drugs that prolong the QT interval. Electrolyte disturbances including hypokalemia and hypomagnesemia have been reported with laxative abuse and are known risk factors for torsade de pointes associated with QT interval prolongation.
MANAGEMENT: Patients treated with drugs that prolong the QT interval should exercise caution when self-medicating with laxatives. The recommended dosage and duration of use should not be exceeded. Patients treated with lactulose for more than six months should be monitored periodically for electrolyte imbalance. Patients should be advised to seek prompt medical attention if they experience symptoms that could indicate the occurrence of torsade de pointes such as dizziness, lightheadedness, fainting, palpitation, irregular heart rhythm, shortness of breath, or syncope.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Chin RL "Laxative-induced hypokalemia." Ann Emerg Med 32 (1998): 517-8
- Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."
- Schaefer DC, Cheskin LJ "Constipation in the elderly." Am Fam Physician 58 (1998): 907-14
- Muller-Lissner SA "Adverse effects of laxatives: fact and fiction." Pharmacology 47 (1993): 138-45
Generic Name: aluminum hydroxide / magnesium hydroxide / simethicone
Brand name: Di-Gel Liquid, Mylanta, Almacone, Gelusil, Mag-al Plus, Mi-Acid, Milantex, Mintox, Mylanta Maximum Strength, Rulox, Mylanta Fast Acting, Mylanta DS Fast Acting, Maalox Plus, Masanti DS, Masanti II, Masanti, Alamag Plus, Mi-Acid II, Almacone-2, Mintox Plus, Mylagen, Mylagen-II, Magaant, Ri-Mox Plus, Rulox Plus, Di-Gel, Ri-Gel II, Uni-Lan, Uni-Lan II, Urban, Urban DS, Maldroxal Plus, Maalox Plus Extra Strength, Tempo, Maalox Max, Maalox, Aldroxicon I, Aldroxicon II, Maalox Antacid Antigas Regular Strength, Mintox Extra Strength, Mintox Maximum Strength, Comfort Gel Original, Comfort Gel Extra Strength, Mylanta Maximum Strength Cherry, Maalox Max Wild Berry, Maalox Advanced Maximum Strength, Milantex Maximum Strength, Maalox Advanced Regular Strength, Geri-Lanta, Mag-al Plus XS, Mylanta Maximum Strength Vanilla Caramel, Mi-Acid Maximum Strength
Synonyms: n.a.
Generic Name: methadone
Brand name: Dolophine, Methadose, Methadose Sugar-Free, Diskets
Synonyms: Methadone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Di-Gel Liquid-Methadose
- Di-Gel Liquid-Methadose (Methadone Oral Concentrate)
- Di-Gel Liquid-Methadose (Methadone Tablets for Oral Suspension)
- Di-Gel Liquid-Methadose (Methadone Tablets)
- Di-Gel Liquid-Methadose Conc
- Di-Gel Liquid-Methadose Disp
- Methadone Tablets for Oral Suspension-Di-Gon II
- Methadone Tablets for Oral Suspension-DiaBeta
- Methadone Tablets for Oral Suspension-DiabetAid Anti-Itch Topical
- Methadone Tablets for Oral Suspension-DiabetAid Antifungal Foot Bath Topical
- Methadone Tablets for Oral Suspension-Diabetic Tussin
- Methadone Tablets for Oral Suspension-Diabetic Tussin Night Time Formula