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Diabinese and Zyloprim

Determining the interaction of Diabinese and Zyloprim and the possibility of their joint administration.

Check result:

Diabinese <> Zyloprim

Relevance: 01.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Allopurinol may decrease the renal excretion and prolong the half-life of chlorpropamide. The clinical significance is unknown. Patients should be advised to regularly monitor their blood sugar, counseled on how to recognize and treat hypoglycemia (e.g., headache, dizziness, drowsiness, nausea, tremor, hunger, weakness, or palpitations) and to notify their physician if it occurs.

References

Petitpierre B, Perrin L, Rudhardt M, et al "Behaviour of chlorpropamide in renal insufficiency and under the effect of associated drug therapy." Int J Clin Pharmacol 6 (1972): 120-4

Diabinese

Generic Name: chlorpropamide

Brand name: Diabinese

Synonyms: n.a.

What is Diabinese?

Zyloprim

Generic Name: allopurinol

Brand name: Zyloprim, Lopurin, Aloprim

Synonyms: n.a.

What is Zyloprim?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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