Dialyvite and Telotristat Etiprate

• Generic Name: multivitamin with iron
• Dosage Forms: tablet, coated
• Other Brand Names:

  Fero-Folic 500, Theragran Hematinic, Ultra Enerforce

Diacomit (stiripentol) is a prescription medicine used to treat seizures associated with Dravet syndrome. Dravet syndrome is a rare chronic form of epilepsy that begins in the first year of life and causes frequent or prolonged seizures.

Diacomit is used along with clobazam for use in adults and children at least 2 years old.

It is not known if Diacomit is safe and effective in children under 2 years of age.

There is no clinical data to support the use of Diacomit alone to treat Dravet syndrome.

• Generic Name: telotristat
• Dosage Forms: n.a.
• Other Brand Names: Xermelo

Used (in combination with somatostatin analog therapy) for treatment of carcinoid syndrome diarrhea inadequately controlled by somatostatin analog therapy alone (designated an orphan drug by FDA for the treatment of carcinoid syndrome in patients with neuroendocrine tumors).

Carcinoid syndrome, a condition associated with serotonin overproduction, is characterized by flushing, diarrhea, wheezing, occasionally congestive heart failure, and various other manifestations. Although somatostatin analogs (e.g., octreotide, lanreotide) are standard treatment for carcinoid syndrome and are effective initially in most patients, some patients may not respond adequately or may develop recurrent symptoms, including diarrhea, despite therapy.

In clinical studies, telotristat ethyl reduced the frequency of daily bowel movements in patients with carcinoid syndrome diarrhea. Reductions in other symptoms of carcinoid syndrome (e.g., abdominal pain, flushing) not observed.