Diamox and Primidone

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using acetaZOLAMIDE together with primidone may decrease the effects of primidone. Contact your doctor if your condition changes or you experience loss of seizure control. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Several case reports suggest that primidone absorption may be decreased or delayed when acetazolamide is coadministered. Plasma levels of primidone and its two metabolites may be decreased, as may seizure control.

MANAGEMENT: Patients should be monitored for loss of seizure control. If an interaction is suspected or observed, it may be necessary to discontinue acetazolamide, to implement alternative antiseizure therapy, or to do both.

Diamox

Generic Name: acetazolamide

Brand name: Diamox, Diamox Sequels

Synonyms: n.a.

What is Diamox?

Primidone

Generic Name: primidone

Brand name: Mysoline

Synonyms: n.a.

What is Primidone?