Diamox Sequels and Sylvant

• Generic Name: acetazolamide
• Dosage Forms: n.a.
• Other Brand Names: Diamox, Diamox Sequels

Diamox Sequels reduces the activity of a protein in your body called carbonic anhydrase. Blocking this protein can help reduce the build-up of certain fluids in the body.

Diamox Sequels is used in people with certain types of glaucoma to reduce the amount of fluid in the eye, which decreases pressure inside the eye.

Diamox Sequels is also used as a diuretic ("water pill") in people with congestive heart failure, to reduce the build-up of fluid in the body. This build-up is called edema.

Diamox Sequels is also used to treat certain types of seizures, and to treat or prevent altitude sickness.

Diamox Sequels may also be used for purposes not listed in this medication guide.

• Generic Name: siltuximab
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Sylvant

Sylvant (siltuximab) inhibits a certain protein in the body called interleukin-6 (IL-6). High levels of IL-6 can cause an overgrowth of cells in the lymph system (part of your immune system).

Sylvant is used to treat Multicentric Castleman's Disease (MCD). MCD is a rare condition in which the body produces too much of a certain type of white blood cell. MCD can increase your risk of certain cancers by changing the way your immune system works.

Sylvant is not for use in people who have human immunodeficiency virus (HIV) or human herpesvirus-8.