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Diamox Sequels and Tofranil injection

Determining the interaction of Diamox Sequels and Tofranil injection and the possibility of their joint administration.

Check result:

Diamox Sequels <> Tofranil injection

Relevance: 20.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Acetazolamide may decrease urinary excretion of tricyclic antidepressants by alkalinizing the urine. This interaction is unlikely to be clinically important.

References

Gram LF, Kofod B, Christiansen J, Rafaelsen OJ "Imipramine metabolism: pH-dependent distribution and urinary excretion." Clin Pharmacol Ther 12 (1971): 239-44

Diamox Sequels

Generic Name: acetazolamide

Brand name: Diamox, Diamox Sequels

Synonyms: n.a.

What is Diamox Sequels?

Tofranil injection

Generic Name: imipramine

Brand name: Tofranil, Tofranil-PM

Synonyms: Tofranil

What is Tofranil injection?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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