Diastat Pediatric and Fosamprenavir Tablets
Determining the interaction of Diastat Pediatric and Fosamprenavir Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Fosamprenavir may increase the blood levels and effects of diazePAM. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience increased side effects or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with amprenavir or its prodrug, fosamprenavir, may increase the plasma concentrations of drugs that are substrates of the CYP450 3A4 isoenzyme. The mechanism is decreased clearance due to inhibition of CYP450 3A4 activity by amprenavir.
MANAGEMENT: Caution is advised if amprenavir must be used concurrently with medications that undergo metabolism by CYP450 3A4, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever amprenavir is added to or withdrawn from therapy.
- "Product Information. Agenerase (amprenavir)." Glaxo Wellcome, Research Triangle Pk, NC.
- "Product Information. Lexiva (fosamprenavir)." GlaxoSmithKline, Research Triangle Park, NC.
Generic Name: diazepam
Brand name: Diastat AcuDial, Diastat Pediatric, Diastat, Valium, Diazepam Intensol, Zetran
Synonyms: n.a.
Generic Name: fosamprenavir
Brand name: Lexiva, Telzir
Synonyms: Fosamprenavir
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diastat Pediatric-Fosaprepitant
- Diastat Pediatric-Fosaprepitant Injection
- Diastat Pediatric-Fosaprepitant Intravenous
- Diastat Pediatric-Foscarnet
- Diastat Pediatric-Foscarnet Intravenous
- Diastat Pediatric-Foscarnet Sodium
- Fosamprenavir Tablets-Diatrizoate Injection
- Fosamprenavir Tablets-Diatrizoate Meglumine
- Fosamprenavir Tablets-Diatrizoate Meglumine and Diatrizoate Sodium
- Fosamprenavir Tablets-Diatrizoate Meglumine and Iodipamide Meglumine
- Fosamprenavir Tablets-Diatx Zn
- Fosamprenavir Tablets-Diazepam