Diastat Pediatric and Nelfinavir Mesylate
Determining the interaction of Diastat Pediatric and Nelfinavir Mesylate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Nelfinavir may increase the blood levels and effects of diazePAM. This can increase the risk of side effects including excessive drowsiness and breathing difficulties. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Nelfinavir competitively inhibits the CYP450 3A4 isoenzyme and may interfere with the metabolism of some benzodiazepines.
MANAGEMENT: Caution is advised if benzodiazepines are administered with nelfinavir. Patients should be monitored for the possibility of potentially serious and/or life threatening events (e.g. prolonged sedation, respiratory depression) associated with the accumulation of these agents.
- "Product Information. Viracept (nelfinavir)." Agouron Pharma Inc, La Jolla, CA.
Generic Name: diazepam
Brand name: Diastat AcuDial, Diastat Pediatric, Diastat, Valium, Diazepam Intensol, Zetran
Synonyms: n.a.
Generic Name: nelfinavir
Brand name: Viracept
Synonyms: Nelfinavir
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diastat Pediatric-Nelfinavir Oral Powder
- Diastat Pediatric-Nelfinavir Tablets
- Diastat Pediatric-Nembutal
- Diastat Pediatric-Nembutal Sodium injection
- Diastat Pediatric-Neo DM
- Diastat Pediatric-Neo-Fradin
- Nelfinavir Mesylate-Diatrizoate Injection
- Nelfinavir Mesylate-Diatrizoate Meglumine
- Nelfinavir Mesylate-Diatrizoate Meglumine and Diatrizoate Sodium
- Nelfinavir Mesylate-Diatrizoate Meglumine and Iodipamide Meglumine
- Nelfinavir Mesylate-Diatx Zn
- Nelfinavir Mesylate-Diazepam