Diastat Pediatric and Soliris

• Generic Name: diazepam
• Dosage Forms: n.a.
• Other Brand Names: Diastat AcuDial, Diastat Pediatric, Diastat, Valium, Diazepam Intensol, Zetran

Diazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Diazepam affects chemicals in the brain that may be unbalanced in people with seizures.

Diastat Pediatric (for use in the rectum) is used to treat occasionally increased seizures (cluster seizures) in people with epilepsy who also routinely take other anti-convulsants. This medicine is not for long-term daily use to prevent seizures.

Diastat Pediatric may also be used for purposes not listed in this medication guide.

• Generic Name: eculizumab
• Dosage Forms: injection, solution, concentrate
• Other Brand Names: Soliris

Soliris (eculizumab) is a monoclonal antibody. Eculizumab binds to proteins in the blood that can destroy red blood cells in people with genetic conditions that affect the natural defenses of red blood cells.

Soliris is used to prevent the breakdown of red blood cells in adults with paroxysmal nocturnal hemoglobinuria (PNH).

Soliris is also used to treat a rare chronic blood disease called atypical hemolytic uremic syndrome (aHUS) in adults and children who weigh at least 11 pounds (5 kilograms).

Soliris is also used to treat myasthenia gravis in adults.

Soliris is also used to treat neuromyelitis optica spectrum disorder (NMOSD) in adults.

Soliris is available only under a special program. You must be registered in the program and understand the risks and benefits of this medicine.