Diazepam Intensol and Marcaine/Epinephrine PF
Determining the interaction of Diazepam Intensol and Marcaine/Epinephrine PF and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using diazePAM together with bupivacaine can increase nervous system side effects such as dizziness, drowsiness, and confusion. Avoid activities requiring mental alertness such as driving or operating hazardous machinery until the effects of these medications have worn off. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
Professional:MONITOR: The concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants.
MANAGEMENT: Caution is advised during concurrent use. Patients should be monitored for potentially excessive or prolonged CNS depression and other CNS adverse effects. Dosage adjustments may be required.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: diazepam
Brand name: Diazepam Intensol, Diastat, Diastat AcuDial, Diastat Pediatric, Valium, Zetran
Synonyms: n.a.
Generic Name: bupivacaine / epinephrine
Brand name: Marcaine/Epinephrine, Marcaine/Epinephrine PF, Sensorcaine-MPF/EPINEPHrine, Sensorcaine/EPINEPHrine
Synonyms: Marcaine/Epinephrine, Marcaine with Epinephrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diazepam Intensol-Mardrops-EX
- Diazepam Intensol-Margesic
- Diazepam Intensol-Margesic Oral
- Diazepam Intensol-Marinol
- Diazepam Intensol-Marlissa
- Diazepam Intensol-Marnatal-F
- Marcaine/Epinephrine PF-Diazepam Oral Concentrate
- Marcaine/Epinephrine PF-Diazepam Oral Solution
- Marcaine/Epinephrine PF-Diazepam Oral Solution Concentrate
- Marcaine/Epinephrine PF-Diazepam rectal
- Marcaine/Epinephrine PF-Diazepam Rectal Gel
- Marcaine/Epinephrine PF-Diazepam Solution