Diclofenac Capsules and Sucralfate
Determining the interaction of Diclofenac Capsules and Sucralfate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Sucralfate may delay or decrease the pharmacologic effects of oral diclofenac. The mechanism may be related to reduced absorption. Data have conflicting and some studies suggest that sucralfate may have a protective effect on the gastric mucosa when taken with NSAIDs. Patients may be advised to take diclofenac 2 hours before or 6 hours after sucralfate if the interaction is to be avoided.
- Pedrazzoli Junior J, Pierossi M de A, Muscara MN, Dias HF, da Silva CM, Mendes FD, de Nucci G "Short-term sucralfate administration alters potassium diclofenac absorption in healthy male volunteers." Br J Clin Pharmacol 43 (1997): 104-8
Generic Name: diclofenac
Brand name: Cambia, Cataflam, Voltaren-XR, Zipsor, Zorvolex, Voltaren, Dyloject, also Cambia
Synonyms: Diclofenac, Diclofenac (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diclofenac Capsules-Sucralfate Oral Suspension
- Diclofenac Capsules-Sucralfate Suspension
- Diclofenac Capsules-Sucralfate Tablet
- Diclofenac Capsules-Sucralfate Tablets
- Diclofenac Capsules-Sucrets 4-Hour Cough Drops
- Diclofenac Capsules-Sucroferric oxyhydroxide
- Sucralfate-Diclofenac Cream
- Sucralfate-Diclofenac Delayed-Release Tablets
- Sucralfate-Diclofenac epolamine
- Sucralfate-Diclofenac Epolamine Patch
- Sucralfate-Diclofenac Extended Release Tablets 100mg
- Sucralfate-Diclofenac Extended-Release Tablets