Diclofenac Sodium and Phenobarbital Oral Solution
Determining the interaction of Diclofenac Sodium and Phenobarbital Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Phenobarbital toxicity has been reported in a patient following initiation of diclofenac. The mechanism and clinical significance of this possible interaction is unknown. If these two drugs must be coadministered, the patient should be observed closely for phenobarbital toxicity such as slowness, ataxia, nystagmus, reduced reflexes and coma. Phenobarbital serum concentrations may need to be more closely monitored.
- "Product Information. Arthrotec (diclofenac-misoprostol)." Searle, Skokie, IL.
Generic Name: diclofenac
Brand name: Cambia, Cataflam, Voltaren-XR, Zipsor, Zorvolex, Voltaren, Dyloject, also Cambia
Synonyms: Diclofenac, Diclofenac (Systemic)
Generic Name: phenobarbital
Brand name: Solfoton, Luminal
Synonyms: Phenobarbital, PHENobarbital
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diclofenac Sodium-Phenobarbital Sodium
- Diclofenac Sodium-Phenobarbital Sodium Injection
- Diclofenac Sodium-Phenobarbital Tablets
- Diclofenac Sodium-Phenobarbital with Belladonna Alkaloids Elixir
- Diclofenac Sodium-Phenohytro
- Diclofenac Sodium-Phenohytro Elixir
- Phenobarbital Oral Solution-Diclofenac Sodium topical
- Phenobarbital Oral Solution-Diclofenac Sodium Topical Solution
- Phenobarbital Oral Solution-Diclofenac Tablets
- Phenobarbital Oral Solution-Diclofenac topical
- Phenobarbital Oral Solution-Diclofenac Topical Patch
- Phenobarbital Oral Solution-Diclofenac Topical Solution