Didanosine and Ranitidine
Determining the interaction of Didanosine and Ranitidine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Ranitidine may slightly increase the bioavailability of didanosine by increasing gastric pH. This interaction is unlikely to be clinically significant.
- Knupp CA, Graziano FM, Dixon RM, Barbhaiya RH "Pharmacokinetic-interaction study of didanosine and ranitidine in patients seropositive for human immunodeficiency virus." Antimicrob Agents Chemother 36 (1992): 2075-9
- "Product Information. Videx (didanosine)." Bristol-Myers Squibb, Princeton, NJ.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Didanosine-Ranitidine Capsule
- Didanosine-Ranitidine Hydrochloride
- Didanosine-Ranitidine Injection
- Didanosine-Ranitidine Suspension
- Didanosine-Ranitidine Syrup
- Didanosine-Ranitidine Tablets
- Ranitidine-Didanosine Delayed-Release Enteric-Coated Capsules
- Ranitidine-Didanosine Oral Solution
- Ranitidine-Didanosine Tablet, for suspension
- Ranitidine-Didrex
- Ranitidine-Didronel
- Ranitidine-Dienogest and estradiol