Didanosine Oral Solution and Kaletra

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

The following interaction applies only if you are taking lopinavir-ritonavir (brand name Kaletra) in a solution formulation: didanosine should not be taken at the same time as lopinavir-ritonavir oral solution. This is because lopinavir-ritonavir oral solution must be taken with food to enhance absorption, whereas food interferes with the absorption of didanosine. You should take didanosine on an empty stomach one hour before or two hours after lopinavir-ritonavir oral solution. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

ADJUST DOSING INTERVAL: Since lopinavir-ritonavir oral solution must be taken with food, simultaneous administration with didanosine may interfere with the gastrointestinal absorption of didanosine, which should be taken on an empty stomach.

MANAGEMENT: When prescribed in combination with lopinavir-ritonavir oral solution, didanosine should be administered on an empty stomach one hour before or two hours after lopinavir-ritonavir oral solution, which is to be taken with food. Lopinavir-ritonavir tablets can be administered simultaneously with didanosine without food.

Didanosine Oral Solution

Generic Name: didanosine

Brand name: Videx, Videx EC

Synonyms: Didanosine

What is Didanosine Oral Solution?

Kaletra

Generic Name: lopinavir / ritonavir

Brand name: Kaletra

Synonyms: n.a.

What is Kaletra?