Didanosine Tablet, for suspension and Pentamidine Injection
Determining the interaction of Didanosine Tablet, for suspension and Pentamidine Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using pentamidine together with didanosine. This can cause inflammation of your pancreas. Contact your doctor if you experience severe pain in your upper stomach spreading to your back, fast heart rate, nausea and vomiting, diarrhea, loss of appetite, and low fever. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Coadministration of intravenous pentamidine with didanosine or zalcitabine may increase the risk of pancreatitis. These drugs have individually been associated with pancreatitis and additive toxicity may occur during concomitant use. Fatalities have been reported.
MANAGEMENT: The manufacturer recommends that the antiretroviral drugs should be interrupted, if clinically feasible, when treatment with intravenous pentamidine is initiated. If concomitant use cannot be avoided, patients should be closely monitored for clinical and laboratory signs of pancreatitis.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: didanosine
Brand name: Videx, Videx EC
Synonyms: Didanosine
Generic Name: pentamidine
Brand name: Nebupent, Pentam 300, Pentam
Synonyms: Pentamidine, Pentamidine (Oral Inhalation)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Didanosine Tablet, for suspension-Pentamidine Isethionate
- Didanosine Tablet, for suspension-Pentamycetin Ophthalmic Solution 0.25%
- Didanosine Tablet, for suspension-Pentamycetin Ophthalmic Solution 0.5%
- Didanosine Tablet, for suspension-Pentasa
- Didanosine Tablet, for suspension-Pentasa Rectal
- Didanosine Tablet, for suspension-Pentazocine
- Pentamidine Injection-Didrex
- Pentamidine Injection-Didronel
- Pentamidine Injection-Dienogest and estradiol
- Pentamidine Injection-Diethylene Triamine Penta-Acetic Acid
- Pentamidine Injection-Diethylpropion
- Pentamidine Injection-Diethylpropion Controlled-Release Tablets