Didanosine Tablet, for suspension and Ritonavir Tablets
Determining the interaction of Didanosine Tablet, for suspension and Ritonavir Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration of ritonavir (600 mg every 12 hours) and didanosine (200 mg every 12 hours) has produced a 13% decrease in the area under the plasma concentration-time curve of didanosine. The plasma level of ritonavir was not affected. This interaction is likely to be of minimal clinical significance and dosage adjustments for didanosine are probably not necessary.
- Cato A, Qian J, Carothers L, et al. "Evaluation of the pharmacokinetic interaction between ritonavir and didanosine." Clin Pharmacol Ther 59 (1996): 144
Generic Name: didanosine
Brand name: Videx, Videx EC
Synonyms: Didanosine
Generic Name: ritonavir
Brand name: Norvir, Norvir Soft Gelatin
Synonyms: Ritonavir
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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