Differin Lotion and Doxylamine Succinate

• Generic Name: adapalene topical
• Dosage Forms: gel, lotion
• Other Brand Names: Differin, Plixda

Differin (adapalene) is a topical medicine (a medication that is applied to the surface of the skin) similar to vitamin A. It helps the skin to renew itself.

Differin is used to treat severe acne in people who are at least 12 years old. It works by decreasing acne formation.

Differin may also be used for purposes not listed in this medication guide.

• Generic Name: doxylamine
• Dosage Forms: n.a.
• Other Brand Names: Unisom, Nytol Maximum Strength, Aldex AN, Nitetime Sleep-Aid, Sleep Aid

Self-medication for short-term management of insomnia, particularly in individuals who have difficulty falling asleep.

Safety and efficacy not fully established; however, FDA states that, pending further accumulation of data, doxylamine-containing nighttime sleep aids approved for this use may continue to be marketed in the US.

Used in fixed combination with pyridoxine for treatment of nausea and vomiting of pregnancy in women not responding to conservative management.

Not studied in patients with hyperemesis gravidarum.

Temporary relief of rhinorrhea, sneezing, lacrimation, itching eyes, or oronasopharyngeal itching associated with allergic rhinitis (e.g., hay fever) or other upper respiratory allergies.