Digox Tablets and Etravirine

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Etravirine may increase the blood levels and effects of digoxin. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, as these may be signs and symptoms of excessive digoxin levels. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration of digoxin with etravirine may increase serum digoxin concentrations. The mechanism is unknown, but etravirine inhibition of p-glycoprotein-mediated transport may be involved.

MANAGEMENT: Caution and monitoring of serum digoxin levels are advised during concomitant use. The lowest dose of digoxin is recommended at initiation of digoxin therapy in patients receiving etravirine. Dose adjustments are not necessary upon initiation of etravirine therapy in patients who are stabilized on digoxin. Digoxin levels should be monitored and the dose titrated accordingly, as necessary. Patients should be advised to notify their physician if they experience potential signs and symptoms of digoxin toxicity such as nausea, anorexia, visual disturbances, slow pulse, or irregular heartbeats.

Digox Tablets

Generic Name: digoxin

Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin

Synonyms: Digox (Oral)

What is Digox Tablets?

Etravirine

Generic Name: etravirine

Brand name: Intelence

Synonyms: n.a.

What is Etravirine?