Digox Tablets and Hydrocodone, Pseudoephedrine, and Guaifenesin
Determining the interaction of Digox Tablets and Hydrocodone, Pseudoephedrine, and Guaifenesin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using digoxin together with pseudoephedrine may occasionally cause an irregular heart rhythm. Patients with heart disease should generally consult with their doctor before using pseudoephedrine or similar medications, since they can affect heart rate and blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of sympathomimetic agents and cardiac glycosides may increase the risk of cardiac arrhythmias. The mechanism of this interaction is not known. Increased ectopic pacemaker activity has been reported to occur in patients taking digoxin in combination with pseudoephedrine.
MANAGEMENT: Caution should be exercised if these two drugs are coadministered. Electrocardiogram monitoring (ECG) is recommended. The use of epinephrine (adrenaline) with high doses of digitalis glycosides is not recommended.
- "Product Information. Claritin-D (loratadine-pseudoephedrine)." Schering-Plough, Liberty Corner, NJ.
- "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
- "Product Information. Epinephrine Hydrochloride Injection (epinephrine)." Abbott Pharmaceutical, Abbott Park, IL.
- "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Lanoxin (digoxin)." Glaxo Wellcome, Research Triangle Park, NC.
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: Digox (Oral)
Generic Name: guaifenesin / hydrocodone / pseudoephedrine
Brand name: Entex HC, Hycofenix, Su-Tuss HD Elixir, Entuss-D JR, Decotuss-HD, Vanex Expectorant, Tussadur-HD, Duratuss HD, Tussend Expectorant, Detussin Expectorant, Tussgen Expectorant, SRC Expectorant, Nalex Expectorant, Deconamine CX, Poly-Tussin XP, Entuss-D, Hydrotussin HD, KG-Tuss HD, Medtuss HD, Spantuss HD, Vanacon, Tussafin Liquid, Hytussin Expectorant, Drituss HD, Hydro-Tuss XP, Dynex HD, Pseudatex HC
Synonyms: Guaifenesin, hydrocodone, and pseudoephedrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Digox Tablets-Hydrocortisone
- Digox Tablets-Hydrocortisone (Systemic)
- Digox Tablets-Hydrocortisone 2.5%
- Digox Tablets-Hydrocortisone Acetate
- Digox Tablets-Hydrocortisone Acetate topical
- Digox Tablets-Hydrocortisone Acetate, Pramoxine Rectal Cream, and Diosmiplex Tablets
- Hydrocodone, Pseudoephedrine, and Guaifenesin-Digoxin
- Hydrocodone, Pseudoephedrine, and Guaifenesin-Digoxin immune FAB
- Hydrocodone, Pseudoephedrine, and Guaifenesin-Digoxin Immune Fab (Ovine)
- Hydrocodone, Pseudoephedrine, and Guaifenesin-Digoxin Injection
- Hydrocodone, Pseudoephedrine, and Guaifenesin-Digoxin Intravenous
- Hydrocodone, Pseudoephedrine, and Guaifenesin-Digoxin Oral Solution