Digox Tablets and Prilocaine with Epinephrine Injection
Determining the interaction of Digox Tablets and Prilocaine with Epinephrine Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using digoxin together with EPINEPHrine may occasionally cause an irregular heart rhythm. Patients with heart disease should generally consult with their doctor before using EPINEPHrine or similar medications, since they can affect heart rate and blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of sympathomimetic agents and cardiac glycosides may increase the risk of cardiac arrhythmias. The mechanism of this interaction is not known. Increased ectopic pacemaker activity has been reported to occur in patients taking digoxin in combination with pseudoephedrine.
MANAGEMENT: Caution should be exercised if these two drugs are coadministered. Electrocardiogram monitoring (ECG) is recommended. The use of epinephrine (adrenaline) with high doses of digitalis glycosides is not recommended.
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- "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
- "Product Information. Epinephrine Hydrochloride Injection (epinephrine)." Abbott Pharmaceutical, Abbott Park, IL.
- "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
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- "Product Information. Lanoxin (digoxin)." Glaxo Wellcome, Research Triangle Park, NC.
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: Digox (Oral)
Generic Name: epinephrine / prilocaine
Brand name: Citanest Forte Dental
Synonyms: Prilocaine and Epinephrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Digox Tablets-Prilolid
- Digox Tablets-Prilosec
- Digox Tablets-Prilosec (Omeprazole Delayed-Release Capsules)
- Digox Tablets-Prilosec (Omeprazole Powder for Oral Suspension)
- Digox Tablets-Prilosec OTC
- Digox Tablets-Prilovix Cream
- Prilocaine with Epinephrine Injection-Digoxin
- Prilocaine with Epinephrine Injection-Digoxin immune FAB
- Prilocaine with Epinephrine Injection-Digoxin Immune Fab (Ovine)
- Prilocaine with Epinephrine Injection-Digoxin Injection
- Prilocaine with Epinephrine Injection-Digoxin Intravenous
- Prilocaine with Epinephrine Injection-Digoxin Oral Solution