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Digox Tablets and Tequin

Determining the interaction of Digox Tablets and Tequin and the possibility of their joint administration.

Check result:
Digox Tablets <> Tequin
Relevance: 12.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Gatifloxacin may increase the blood levels and effects of digoxin. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, as these may be signs and symptoms of excessive digoxin levels. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Some fluoroquinolones may significantly increase plasma digoxin levels. The mechanism has not been reported.

MANAGEMENT: Clinical and laboratory monitoring for altered digoxin efficacy and safety is recommended during coadministration. Patients should be advised to notify their physician if they experience signs of digoxin toxicity such as nausea, anorexia, visual disturbances, slow pulse, or irregular heartbeats. Dose adjustments may be required if an interaction is suspected.

References
  • "Product Information. Tequin (gatifloxacin)" Bristol-Myers Squibb, Princeton, NJ.
  • "Product Information. Penetrex (enoxacin)." Rhone-Poulenc Rorer, Collegeville, PA.
Digox Tablets

Generic Name: digoxin

Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin

Synonyms: Digox (Oral)

Tequin

Generic Name: gatifloxacin

Brand name: Tequin, Tequin Teqpaq

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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