Digoxin and Fluvastatin Sodium
Determining the interaction of Digoxin and Fluvastatin Sodium and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that fluvastatin may slightly increase the plasma clearance of digoxin by an unknown mechanism. The clinical significance of this interaction is unknown. Digoxin serum concentrations and clinical response should be monitored during concomitant therapy. Patients should be advised to notify their physician if they experience nausea, anorexia, visual disturbances, slow pulse, or irregular heartbeats.
- "Product Information. Lescol (fluvastatin)." Novartis Pharmaceuticals, East Hanover, NJ.
- Deslypere JP "Clinical implications of the biopharmaceutical properties of fluvastatin." Am J Cardiol 73 (1994): d12-7
- Garnett WR, Venitz J, Wilkens RC, Dimenna G "Pharmacokinetic effects of fluvastatin in patients chronically receiving digoxin." Am J Med 96 (1994): s84-6
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: n.a.
Generic Name: fluvastatin
Brand name: Lescol, Lescol XL
Synonyms: Fluvastatin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Digoxin-Fluvirin
- Digoxin-Fluvirin 2015-2016 Formula
- Digoxin-Fluvirin injection
- Digoxin-Fluvoxamine
- Digoxin-Fluvoxamine ER Capsules
- Digoxin-Fluvoxamine Extended-Release Capsules
- Fluvastatin Sodium-Digoxin immune FAB
- Fluvastatin Sodium-Digoxin Immune Fab (Ovine)
- Fluvastatin Sodium-Digoxin Injection
- Fluvastatin Sodium-Digoxin Intravenous
- Fluvastatin Sodium-Digoxin Oral Solution
- Fluvastatin Sodium-Digoxin oral/injection