Digoxin and Paromomycin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Oral neomycin has been shown to decrease the absorption of oral digoxin. The effects of oral paromomycin and kanamycin are not known. The proposed mechanism is a neomycin-induced malabsorption syndrome resulting in reduced absorption of drugs. This effect may be offset by a subsequent decrease in digoxin metabolism. During concomitant therapy with any of these antibiotics, digoxin serum concentrations and efficacy should be monitored. Patients should be advised to notify their physician if they experience a worsening of their heart symptoms.

Digoxin

Generic Name: digoxin

Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin

Synonyms: n.a.

What is Digoxin?

Paromomycin

Generic Name: paromomycin

Brand name: Humatin, Paromycin

Synonyms: n.a.

What is Paromomycin?