Digoxin and Topiramate Extended-Release Sprinkle Capsules

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

In a single-dose study, the serum digoxin area under the curve was decreased by 12% when coadministered with topiramate. The mechanism and clinical significance of this interaction is unknown. Serum digoxin levels and clinical response should be monitored. Patients should be advised to notify their physician if they experience worsening heart symptoms.

Digoxin

Generic Name: digoxin

Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin

Synonyms: n.a.

What is Digoxin?

Topiramate Extended-Release Sprinkle Capsules

Generic Name: topiramate

Brand name: Qudexy XR Sprinkle, Topamax, Topamax Sprinkle, Trokendi XR, Topiragen, Qudexy XR

Synonyms: Topiramate

What is Topiramate Extended-Release Sprinkle Capsules?