Digoxin and Trazodone Oral
Determining the interaction of Digoxin and Trazodone Oral and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Trazodone may increase serum digoxin levels. The mechanism is unknown and it is not known. If trazodone and digoxin must be used together, close observation for clinical and laboratory evidence of digoxin toxicity is recommended. Patients should be advised to notify their physician if they experience nausea, anorexia, visual changes, slow pulse, or irregular heartbeats.
- Rauch PK, Jenike MA "Digoxin toxicity possibly precipitated by trazodone." Psychosomatics 25 (1984): 334-5
- "Product Information. Desyrel (trazodone)." Bristol-Myers Squibb, Princeton, NJ.
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: n.a.
Generic Name: trazodone
Brand name: Desyrel, Desyrel Dividose, Oleptro
Synonyms: Trazodone, TraZODone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Digoxin-Trazodone Tablets
- Digoxin-Treanda
- Digoxin-Trecator
- Digoxin-Trecator-SC
- Digoxin-Trelegy Ellipta
- Digoxin-Trelstar
- Trazodone Oral-Digoxin immune FAB
- Trazodone Oral-Digoxin Immune Fab (Ovine)
- Trazodone Oral-Digoxin Injection
- Trazodone Oral-Digoxin Intravenous
- Trazodone Oral-Digoxin Oral Solution
- Trazodone Oral-Digoxin oral/injection