Digoxin Injection and Zelnorm
Determining the interaction of Digoxin Injection and Zelnorm and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Tegaserod slightly decreased digoxin plasma concentrations and AUC in a clinical study (n=12); however the changes were considered clinically insignificant. The mechanism is unknown. No action is necessary.
- "Product Information. Zelnorm (tegaserod)." Novartis Pharmaceuticals, East Hanover, NJ.
- Zhou H, Horowitz A, Ledford PC, et al. "The effects of tegaserod (HTF 919) on the pharmacokinetics and pharmacodynamics of digoxin in healthy subjects." J Clin Pharmacol 41 (2001): 1131-9
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: Digoxin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Digoxin Injection-Zema-Pak
- Digoxin Injection-Zembrace SymTouch
- Digoxin Injection-Zembrace SymTouch injection
- Digoxin Injection-Zemdri
- Digoxin Injection-Zemplar
- Digoxin Injection-Zemplar (Paricalcitol Capsules)
- Zelnorm-Digoxin Intravenous
- Zelnorm-Digoxin Oral Solution
- Zelnorm-Digoxin oral/injection
- Zelnorm-Digoxin Tablets
- Zelnorm-Dihydro CP Syrup
- Zelnorm-Dihydrocodeine BPM Phenyleph HCl