Digoxin oral/injection and Xylocaine MPF With Epinephrine
Determining the interaction of Digoxin oral/injection and Xylocaine MPF With Epinephrine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using digoxin together with EPINEPHrine may occasionally cause an irregular heart rhythm. Patients with heart disease should generally consult with their doctor before using EPINEPHrine or similar medications, since they can affect heart rate and blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of sympathomimetic agents and cardiac glycosides may increase the risk of cardiac arrhythmias. The mechanism of this interaction is not known. Increased ectopic pacemaker activity has been reported to occur in patients taking digoxin in combination with pseudoephedrine.
MANAGEMENT: Caution should be exercised if these two drugs are coadministered. Electrocardiogram monitoring (ECG) is recommended. The use of epinephrine (adrenaline) with high doses of digitalis glycosides is not recommended.
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- "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
- "Product Information. Epinephrine Hydrochloride Injection (epinephrine)." Abbott Pharmaceutical, Abbott Park, IL.
- "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Lanoxin (digoxin)." Glaxo Wellcome, Research Triangle Park, NC.
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: Digoxin
Generic Name: epinephrine / lidocaine
Brand name: D-Care 100X, Lignospan Forte, Lignospan Standard, Xylocaine MPF With Epinephrine, Xylocaine With Epinephrine
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Digoxin oral/injection-Xylocaine Topical application
- Digoxin oral/injection-Xylocaine Topical Solution
- Digoxin oral/injection-Xylocaine With Epinephrine
- Digoxin oral/injection-Xylometazoline
- Digoxin oral/injection-Xylometazoline nasal
- Digoxin oral/injection-Xylon
- Xylocaine MPF With Epinephrine-Digoxin Tablets
- Xylocaine MPF With Epinephrine-Dihydro CP Syrup
- Xylocaine MPF With Epinephrine-Dihydrocodeine BPM Phenyleph HCl
- Xylocaine MPF With Epinephrine-Dihydrocodeine, Aspirin, and Caffeine
- Xylocaine MPF With Epinephrine-Dihydroergotamine
- Xylocaine MPF With Epinephrine-Dihydroergotamine injection