Digoxin Oral Solution and NyQuil Severe Cold & Flu
Determining the interaction of Digoxin Oral Solution and NyQuil Severe Cold & Flu and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using digoxin together with phenylephrine may occasionally cause an irregular heart rhythm. Patients with heart disease should generally consult with their doctor before using phenylephrine or similar medications, since they can affect heart rate and blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of sympathomimetic agents and cardiac glycosides may increase the risk of cardiac arrhythmias. The mechanism of this interaction is not known. Increased ectopic pacemaker activity has been reported to occur in patients taking digoxin in combination with pseudoephedrine.
MANAGEMENT: Caution should be exercised if these two drugs are coadministered. Electrocardiogram monitoring (ECG) is recommended. The use of epinephrine (adrenaline) with high doses of digitalis glycosides is not recommended.
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- "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
- "Product Information. Epinephrine Hydrochloride Injection (epinephrine)." Abbott Pharmaceutical, Abbott Park, IL.
- "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Lanoxin (digoxin)." Glaxo Wellcome, Research Triangle Park, NC.
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: Digoxin
Generic Name: acetaminophen / dextromethorphan / doxylamine / phenylephrine
Brand name: Alka-Seltzer Plus Night-Time Cold, Delsym Adult Night Time Multi-Symptom, Mucinex Fast-Max Night Time Cold & Flu, NyQuil Severe Cold & Flu, Tylenol Cold Multi-Symptom Nighttime, Tylenol Warming Cold Multi-Symptom Nighttime, Tylenol Cold Plus Flu Plus Cough Night
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Digoxin Oral Solution-Nystatin
- Digoxin Oral Solution-Nystatin (Oral)
- Digoxin Oral Solution-Nystatin and Triamcinolone
- Digoxin Oral Solution-Nystatin and Triamcinolone Ointment
- Digoxin Oral Solution-Nystatin and triamcinolone topical
- Digoxin Oral Solution-Nystatin Oral Suspension
- NyQuil Severe Cold & Flu-Digoxin oral/injection
- NyQuil Severe Cold & Flu-Digoxin Tablets
- NyQuil Severe Cold & Flu-Dihydro CP Syrup
- NyQuil Severe Cold & Flu-Dihydrocodeine BPM Phenyleph HCl
- NyQuil Severe Cold & Flu-Dihydrocodeine, Aspirin, and Caffeine
- NyQuil Severe Cold & Flu-Dihydroergotamine