Digoxin Tablets and Rubex

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Some cancer drugs like DOXOrubicin can cause damage to the intestinal lining and interfere with the absorption of digoxin. Blood levels and effects of digoxin may be reduced during chemotherapy. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition worsens or you experience increased symptoms of heart failure such as tiredness, swelling, fluid retention, sudden weight gain, difficulty breathing, shortness of breath, irregular heartbeat, or chest pain. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: The use of some antineoplastic agents has been associated with decreased gastrointestinal absorption of digoxin. The suspected mechanism is alteration of the gastrointestinal mucosa. The risk of an interaction is expected to be less with digoxin solution in capsules because absorption occurs rapidly in the upper GI tract.

MANAGEMENT: Digoxin serum levels and effectiveness should be monitored closely following the initiation or discontinuation of antineoplastic agents, and the dosage adjusted as necessary.

Digoxin Tablets

Generic Name: digoxin

Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin

Synonyms: Digoxin

What is Digoxin Tablets?

Rubex

Generic Name: doxorubicin

Brand name: Adriamycin, Adriamycin RDF, Rubex, Adriamycin PFS

Synonyms: Doxorubicin, DOXOrubicin (Conventional)

What is Rubex?