Dihydroergotamine Mesylate and Tadalafil

• Generic Name: dihydroergotamine
• Dosage Forms: n.a.
• Other Brand Names: DHE. 45, Migranal

Acute treatment of migraine attacks (with or without aura) or cluster headaches.

One of several preferred initial therapies in moderate to severe migraines or mild to moderate migraines that respond poorly to NSAIAs.

IV treatment of intractable migraines (e.g., status migrainosus); usually used in combination with IV antiemetic.

Not recommended for management of hemiplegic or basilar migraine or for prophylaxis or chronic daily management of migraine.

Used in combination with low-dose heparin therapy for prevention of postoperative DVT and pulmonary embolism; generally has been replaced by other more effective therapies (e.g., low molecular weight heparin alone, warfarin).

• Generic Name: tadalafil
• Dosage Forms: n.a.
• Other Brand Names: Adcirca, Cialis, Alyq

Tadalafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.

Tadalafil under the name of Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.