Dihydroergotamine Mesylate and Zofran ODT Oral, Oromucosal

• Generic Name: dihydroergotamine
• Dosage Forms: n.a.
• Other Brand Names: DHE. 45, Migranal

Acute treatment of migraine attacks (with or without aura) or cluster headaches.

One of several preferred initial therapies in moderate to severe migraines or mild to moderate migraines that respond poorly to NSAIAs.

IV treatment of intractable migraines (e.g., status migrainosus); usually used in combination with IV antiemetic.

Not recommended for management of hemiplegic or basilar migraine or for prophylaxis or chronic daily management of migraine.

Used in combination with low-dose heparin therapy for prevention of postoperative DVT and pulmonary embolism; generally has been replaced by other more effective therapies (e.g., low molecular weight heparin alone, warfarin).

• Generic Name: ondansetron
• Dosage Forms: tablet, orally disintegrating
• Other Brand Names: Zofran, Zofran ODT, Zuplenz

Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. It is also used to prevent nausea and vomiting that may occur after surgery. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting.

This medicine is available only with your doctor's prescription.