Dihydroergotamine nasal and Sunmark Nicotine Lozenge
Determining the interaction of Dihydroergotamine nasal and Sunmark Nicotine Lozenge and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Nicotine may increase the effects of dihydroergotamine in narrowing the blood vessels and decreasing blood flow. A severe decrease in blood flow to the brain and other parts of the body can lead to dangerous side effects. Contact your doctor immediately if you experience coldness, paleness, discoloration, numbness, tingling, or pain in your hands or feet; muscle pain or weakness; severe or worsening headache; blurred vision; severe abdominal pain; chest pain; or shortness of breath while taking these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Nicotine may cause vasoconstriction in some patients and potentiate the ischemic response to ergot alkaloids. The clinical significance is unknown.
MANAGEMENT: Caution may be advisable when ergot alkaloids are used in combination with nicotine products. Patients should be advised to seek immediate medical attention if they experience potential symptoms of ischemia such as coldness, pallor, cyanosis, numbness, tingling, or pain in the extremities; muscle weakness; severe or worsening headache; visual disturbances; severe abdominal pain; chest pain; and shortness of breath.
- "Product Information. Migranal (dihydroergotamine nasal)." Novartis Pharmaceuticals, East Hanover, NJ.
- "Product Information. Cafergot (caffeine-ergotamine)." Novartis Pharmaceuticals, East Hanover, NJ.
Generic Name: dihydroergotamine
Brand name: DHE. 45, Migranal
Synonyms: Dihydroergotamine (injection), Dihydroergotamine
Generic Name: nicotine
Brand name: Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive, Commit, Habitrol, Nicoderm C-Q, Nicotine System Kit, Nicoderm CQ, Nicotrol Inhaler, Nicotrol NS
Synonyms: Nicotine Gum and Lozenges, Nicotine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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