Dilantin and Triaminic Cough & Runny Nose

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using chlorpheniramine together with phenytoin can increase the effects of phenytoin. Contact your doctor if you experience drowsiness, visual disturbances, change in mental status, nausea, loss of muscle coordination, or involuntary movements. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Toxic serum concentrations of phenytoin and involuntary movements have been reported during coadministration with chlorpheniramine. Symptoms resolved after chlorpheniramine was discontinued. The mechanism of this interaction is not known.

MANAGEMENT: Clinical monitoring of patient response, tolerance, and serum phenytoin concentrations is recommended. Patients should be advised to notify their physician if they experience symptoms of phenytoin toxicity (drowsiness, visual disturbances, change in mental status, nausea, or ataxia) or involuntary movements.

Dilantin

Generic Name: phenytoin

Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt

Synonyms: n.a.

What is Dilantin?

Triaminic Cough & Runny Nose

Generic Name: chlorpheniramine / dextromethorphan

Brand name: Children's NyQuil Cold & Cough, Coricidin HBP Cough & Cold, Dimetapp Long Acting Cough Plus Cold, Robitussin Pediatric Cough & Cold Long-Acting, Scot-Tussin Sugar Free DM, Triaminic Cough & Runny Nose, Effective Strength Cough Syrup, Primatuss 4, Coricidin HBP Cough and Cold, Tricodene Sugar Free, Triaminic Night Time Cough & Runny Nose, Triaminic Cough & Runny Nose Softchews, Robitussin Cough & Cold Long-Acting, Cough & Cold, Coricidin HBP Cough/Cold, QC Cough/Cold, Scot-Tussin DM, Tricodene SF

Synonyms: n.a.

What is Triaminic Cough & Runny Nose?