Dilantin Infatabs and Rifabutin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using rifabutin together with phenytoin may decrease the effects of phenytoin. Contact your doctor if your condition changes or if you experience loss of seizure control. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Rifampin and rifabutin may decrease plasma concentrations and effectiveness of hydantoins by inducing their CYP450 hepatic metabolism.

MANAGEMENT: Close observation for clinical and laboratory evidence of altered hydantoin effect is recommended. Patients should be advised to notify their physician if they experience loss of seizure control. Dosage should be increased as necessary.

Dilantin Infatabs

Generic Name: phenytoin

Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt

Synonyms: Dilantin

What is Dilantin Infatabs?

Rifabutin

Generic Name: rifabutin

Brand name: Mycobutin

Synonyms: n.a.

What is Rifabutin?