Dilantin injection and Ondansetron Oral Solution
Determining the interaction of Dilantin injection and Ondansetron Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using phenytoin together with ondansetron can decrease the effects of ondansetron. Contact your doctor if you experience an increase in nausea and vomiting. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Concomitant use of CYP450 3A4 inducers with ondansetron may result in a reduced antiemetic effect, particularly after the oral administration of ondansetron. The proposed mechanism is induction of the CYP450 3A4 mediated metabolism of ondansetron. The clinical significance is unknown.
MANAGEMENT: Patients should be monitored for reduced antiemetic effects and the ondansetron dose adjusted as necessary.
- "Multum Information Services, Inc. Expert Review Panel"
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: phenytoin
Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt
Synonyms: Dilantin
Generic Name: ondansetron
Brand name: Zofran, Zofran ODT, Zuplenz
Synonyms: Ondansetron
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Dilantin injection-Ondansetron Oral, Injection, Intravenous
- Dilantin injection-Ondansetron Oral, Oromucosal
- Dilantin injection-Ondansetron Orally Disintegrating Tablets
- Dilantin injection-Ondansetron Tablets
- Dilantin injection-One A Day Cholesterol Plus
- Dilantin injection-One A Day Energy
- Ondansetron Oral Solution-Dilantin Kapseals
- Ondansetron Oral Solution-Dilantin-125
- Ondansetron Oral Solution-Dilantin-30
- Ondansetron Oral Solution-Dilatrate-SR
- Ondansetron Oral Solution-Dilaudid
- Ondansetron Oral Solution-Dilaudid (Hydromorphone Injection)