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Dilt-CD and Ethmozine

Determining the interaction of Dilt-CD and Ethmozine and the possibility of their joint administration.

Check result:
Dilt-CD <> Ethmozine
Relevance: 06.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Concomitant administration of diltiazem and moricizine has been reported to increase serum concentrations of moricizine and to decrease serum concentrations of diltiazem. The mechanism of the interaction and clinical significance are unknown. If these drugs are used together, close monitoring for altered effects is strongly recommended when either drug is initiated, stopped, or a dosage adjustment made.

References
  • Shum L, Pieniaszek HJ, Robinson CA, Davidson AF, Widner PJ, Benedek IH, Flamenbaum W "Pharmacokinetic interactions of moricizine and diltiazem in healthy volunteers." J Clin Pharmacol 36 (1996): 1161-8
Dilt-CD

Generic Name: diltiazem

Brand name: Cardizem, Cartia XT, Dilacor XR, Dilt-CD, Diltia XT, Dilt-XR, Diltzac, Matzim LA, Taztia XT, Tiazac, Cardizem CD, Tiazac, Cardizem LA, Tiazac Extended Release Capsules

Synonyms: Diltiazem

Ethmozine

Generic Name: moricizine

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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