Diltiazem CD and Sodium Nitroprusside
Determining the interaction of Diltiazem CD and Sodium Nitroprusside and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:The dosage of nitroprusside required to achieve a given hypotensive response is reduced by an average of 50% when diltiazem is coadministered. The mechanism is unknown. Since the risk of side effects from nitroprusside may be significantly decreased with a lower dose, this interaction may be advantageous.
- Bernard JM, Moren J, Demeure D, Mommeril JL, Pinaud M "Diltiazem reduces the nitroprusside doses for deliberate hypotension." Anesthesiology 77 (1992): a427
Generic Name: diltiazem
Brand name: Cardizem, Cartia XT, Dilacor XR, Dilt-CD, Diltia XT, Dilt-XR, Diltzac, Matzim LA, Taztia XT, Tiazac, Cardizem CD, Tiazac, Cardizem LA, Tiazac Extended Release Capsules
Synonyms: Diltiazem
Generic Name: nitroprusside
Brand name: Nitropress, Nipride RTU
Synonyms: Nitroprusside
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diltiazem CD-Sodium Nitroprusside Injection
- Diltiazem CD-Sodium nitroprusside Intravenous
- Diltiazem CD-Sodium oxybate
- Diltiazem CD-Sodium phenylacetate and benzoate Intravenous
- Diltiazem CD-Sodium Phenylacetate and Sodium Benzoate
- Diltiazem CD-Sodium Phenylacetate and Sodium Benzoate Injection
- Sodium Nitroprusside-Diltiazem Extended Release Tablets
- Sodium Nitroprusside-Diltiazem Hydrochloride
- Sodium Nitroprusside-Diltiazem Injection
- Sodium Nitroprusside-Diltiazem Intravenous
- Sodium Nitroprusside-Diltiazem Long-Acting Capsules
- Sodium Nitroprusside-Diltiazem Long-Acting Tablets