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Diltiazem Extended Release Tablets and NovoLog PenFill

Determining the interaction of Diltiazem Extended Release Tablets and NovoLog PenFill and the possibility of their joint administration.

Check result:

Diltiazem Extended Release Tablets <> NovoLog PenFill

Relevance: 12.08.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

A single case report suggests that diltiazem may decrease the hypoglycemic effect of insulin. The mechanism of interaction is unknown. Diltiazem 180 mg/day reportedly had no effect on glucose levels in normal subjects. In addition, diltiazem 240 to 360 mg/day had no significant effects on glucose control in 23 hypertensive patients with Type II diabetes. While no special precautions appear to be necessary, patients may consider monitoring blood glucose more closely during the first few days or weeks of diltiazem therapy until glucose control is assured.

References

Pershadsingh HA, Grant N, McDonald JM "Association of diltiazem therapy with increased insulin resistance in a patient with type I diabetes mellitus." JAMA 257 (1987): 930-1

Diltiazem Extended Release Tablets

Generic Name: diltiazem

Brand name: Cardizem, Cartia XT, Dilacor XR, Dilt-CD, Diltia XT, Dilt-XR, Diltzac, Matzim LA, Taztia XT, Tiazac, Cardizem CD, Tiazac, Cardizem LA, Tiazac Extended Release Capsules

Synonyms: Diltiazem

What is Diltiazem Extended Release Tablets?

NovoLog PenFill

Generic Name: insulin aspart

Brand name: Fiasp, NovoLog, NovoLog FlexPen, NovoLog PenFill, NovoLOG FlexTouch, Fiasp PenFill, Fiasp FlexTouch

Synonyms: n.a.

What is NovoLog PenFill?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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