Dimaphen DM and Polatuzumab Vedotin-piiq

• Generic Name: brompheniramine / dextromethorphan / phenylephrine
• Dosage Forms: n.a.
• Other Brand Names: Alahist DM, BP Allergy DM, Bromatan-DM, Children's Cold & Cough DM, Cold & Cough Childrens, Dimaphen DM, Dimetapp Cold & Cough, Dimetapp DM Cold & Cough, DuraTan DM, Rynex DM, TL-Hist DM, Tussi-Pres B, Dimetapp DM Cold/Cough, Glenmax PEB DM FORTE, Glenmax PEB DM, LoHist-DM, Niva-Hist DM, TGQ 75PEH/4BRM/15DM

Brompheniramine is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of brompheniramine, dextromethorphan, and phenylephrine is used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.

Dimaphen DM will not treat a cough that is caused by smoking, asthma, or emphysema.

Dimaphen DM may also be used for purposes not listed in this medication guide.

• Generic Name: polatuzumab vedotin
• Dosage Forms: n.a.
• Other Brand Names: Polivy

Polatuzumab vedotin-piiq is a CD79b-directed antibody–drug conjugate indicated in combination with bendamustine and a rituximab product for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma, not otherwise specified, after at least two prior therapies.

Accelerated approval was granted for this indication based on complete response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial.