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Dimercaprol and Ferus Pic-150

Determining the interaction of Dimercaprol and Ferus Pic-150 and the possibility of their joint administration.

Check result:
Dimercaprol <> Ferus Pic-150
Relevance: 13.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Dimercaprol can bind with certain metals such as iron and selenium, forming a complex that is toxic to the kidneys. Products containing iron or selenium should not be used during dimercaprol therapy. If you are currently receiving or have recently received iron polysaccharide, let your doctor know before receiving treatment with dimercaprol. You may need to wait at least 24 hours after the last dose of dimercaprol before you can start or resume iron polysaccharide. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Dimercaprol can form a nephrotoxic chelate with certain metals such as cadmium, iron, and selenium.

MANAGEMENT: Preparations containing iron or selenium salts should not be administered during chelation therapy with dimercaprol and for at least 24 hours after the last dose of dimercaprol.

References
  • Chenoweth MB "Clinical uses of metal-binding drugs." Clin Pharmacol Ther 9 (1968): 365-87
  • "Product Information. BAL in Oil (dimercaprol)." Becton Dickinson, Franklin Lakes, NJ.
  • Seffart G ed. "Drug Dosage in Renal Insufficiency." Dordrecht, South Holland, : Kluwer Academic Publishers (1991):
Dimercaprol

Generic Name: dimercaprol

Brand name: BAL In Oil

Synonyms: n.a.

Ferus Pic-150

Generic Name: iron polysaccharide

Brand name: Ezfe, Ferrex-150, Ferus Pic-150, Iferex 150, Niferex Elixir, NovaFerrum 50, Nu-Iron 150, Poly Iron, ProFe, Myferon 150, Novaferrum, Poly-Iron, Fe-Tinic 150, Ferrex 150 Plus, Niferex-150

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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