Dimetapp ND and Pamidronate Disodium

• Generic Name: loratadine
• Dosage Forms: tablet, orally disintegrating
• Other Brand Names: Alavert, Claritin, Claritin Reditab, Clear-Atadine, Dimetapp ND, Ohm Allergy Relief, QlearQuil All Day & Night, Tavist ND, Wal-itin

Dimetapp ND is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dimetapp ND is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.

Dimetapp ND is also used to treat skin hives and itching in people with chronic skin reactions.

Dimetapp ND may also be used for purposes not listed in this medication guide.

• Generic Name: pamidronate
• Dosage Forms: n.a.
• Other Brand Names: Aredia

Used in conjunction with achievement and maintenance of adequate hydration for the treatment of moderate to severe hypercalcemia associated with malignant neoplasms, with or without bone metastases.

More conservative measures (e.g., hydration alone or combined with loop diuretics) generally used for treatment of mild or asymptomatic hypercalcemia. Corticosteroid therapy may be beneficial in hypercalcemia associated with hematological malignancies.

Consider retreatment in patients with recurrent or refractory disease.

Treatment of moderate to severe Paget’s disease of bone (osteitis deformans) in symptomatic patients with multiple bone involvement [polyostotic] and elevated concentrations of serum alkaline phosphatase and urinary hydroxyproline.

May prevent or slow progression of complications (e.g., deformities, arthritis, fractures, neurologic manifestations, spinal cord compression, heart failure) in patients with Paget’s disease of bone. May not reverse established complications (e.g., severe deformities, deafness).

Treatment in patients refractory to calcitonin or etidronate disodium.

Used as an adjunct to antineoplastic therapy for the treatment of osteolytic bone metastases of breast cancer and osteolytic lesions of multiple myeloma.

Decreases the incidence and delays the development of bone-related complications (e.g., fractures or spinal cord compression, bone deterioration requiring radiotherapy or orthopedic surgery), and reduces bone pain and the need for supplemental analgesic therapy.