Dimethyl sulfoxide Intravesical and Stelara

• Generic Name: dimethyl sulfoxide
• Dosage Forms: n.a.
• Other Brand Names: Cryoserv, Rimso-50

Dimethyl sulfoxide is a purified preparation used in the bladder to relieve the symptoms of the bladder condition called interstitial cystitis. A catheter (tube) or syringe is used to put the solution into the bladder where it is allowed to remain for about 15 minutes. Then, the solution is expelled by urinating.

Interstitial cystitis is the only human use for dimethyl sulfoxide that is approved by the U.S. Food and Drug Administration (FDA).

Claims that dimethyl sulfoxide is effective for treating various types of arthritis, ulcers in scleroderma, muscle sprains and strains, bruises, infections of the skin, burns, wounds, and mental conditions have not been proven.

Although other preparations of dimethyl sulfoxide are available for industrial and veterinary (animal) use, they must not be used by humans, because of their unknown purity. Impurities in these preparations may cause serious unwanted effects in humans. Even if dimethyl sulfoxide is applied to the skin, it is absorbed into the body through the skin and mucous membranes.

Dimethyl sulfoxide is available only with your doctor's prescription.

• Generic Name: ustekinumab
• Dosage Forms: injection, solution
• Other Brand Names: Stelara, Stelara PFS

Stelara (ustekinumab) is an immunosuppressant that reduces the effects of a chemical substance in the body that can cause inflammation.

Stelara is used to treat plaque psoriasis in adults and children who are at least 12 years old. It is also used to treat psoriatic arthritis in adults, and is sometimes given with another medicine called methotrexate.

Stelara is used in adults to treat moderately to severely active Crohn's disease after other medicines have been tried without success.

Stelara is also used in adults to treat moderately to severely active ulcerative colitis.