Dinutuximab Intravenous and Lenalidomide

• Generic Name: dinutuximab
• Dosage Forms: n.a.
• Other Brand Names: Unituxin

Dinutuximab injection is used in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), to treat children with high-risk neuroblastoma (a type of cancer that most often occurs in young children). Dinutuximab is a GD2-binding monoclonal antibody.

Dinutuximab is to be given only by or under the direct supervision of your doctor.

• Generic Name: lenalidomide
• Dosage Forms: n.a.
• Other Brand Names: Revlimid

Lenalidomide is used to treat multiple myeloma (bone marrow cancer), either in combination with another medicine or after stem cell transplant.

Lenalidomide is also used to treat anemia (a lack of red blood cells) in patients with myelodysplastic syndrome caused by an abnormal chromosome. This disorder is also called deletion 5q MDS, because part of chromosome 5 is missing. In people with this disorder, the bone marrow does not produce enough healthy blood cells.

Lenalidomide is also used to treat mantle cell lymphoma, follicular lymphoma, or marginal zone lymphoma, after other medications have been tried without success.

Lenalidomide is available only under a special program. You must be registered in the program and understand the risks and benefits of lenalidomide. You must also agree to use birth control measures as required by the program.

Lenalidomide may also be used for purposes not listed in this medication guide.