Diphenhydramine and magnesium salicylate and Dipivefrin Hydrochloride

• Generic Name: diphenhydramine / magnesium salicylate
• Dosage Forms: n.a.
• Other Brand Names: Doans PM

Diphenhydramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Magnesium salicylate is a nonsteroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates). This medicine works by reducing substances in the body that cause pain, fever, and inflammation.

Diphenhydramine and magnesium salicylate is a combination medicine used to treat back pain that keeps you awake during your normal sleeping hours.

This medicine may also be used for purposes not listed in this medication guide.

• Generic Name: dipivefrin ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Propine

Reduction of elevated IOP in patients with open-angle glaucoma. Used alone or in conjunction with other IOP-lowering drugs. May be used as initial therapy or for control of IOP in those patients who have not responded adequately to other antiglaucoma agents.

May be preferred as an alternative to topical epinephrine in some patients (e.g., those with cardiovascular disease) because of increased intraocular penetration (lower doses are needed) and resultant decreased adverse systemic effects (e.g., cardiovascular effects) compared with epinephrine.

Does not produce miosis, accommodative spasm, blurred vision, or night blindness. Less likely than epinephrine to cause adenochrome staining of contact lenses.

Has been used to reduce IOP in the treatment of other ocular conditions, including ocular hypertension and pseudoexfoliative, low-tension, and secondary (e.g., post-angle closure, pigmentary, traumatic, herpes zoster) glaucomas.