Diphenhydramine and magnesium salicylate and Dolutegravir Sodium and Rilpivirine Hydrochloride

• Generic Name: diphenhydramine / magnesium salicylate
• Dosage Forms: n.a.
• Other Brand Names: Doans PM

Diphenhydramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Magnesium salicylate is a nonsteroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates). This medicine works by reducing substances in the body that cause pain, fever, and inflammation.

Diphenhydramine and magnesium salicylate is a combination medicine used to treat back pain that keeps you awake during your normal sleeping hours.

This medicine may also be used for purposes not listed in this medication guide.

• Generic Name: dolutegravir / rilpivirine
• Dosage Forms: n.a.
• Other Brand Names: Juluca

Treatment of HIV-1 infection in certain antiretroviral-experienced (previously treated) adults.

Use to replace the current regimen only in antiretroviral-experienced adults who are virologically suppressed (i.e., plasma HIV-1 RNA levels <50 copies/mL) on a stable antiretroviral regimen for ≥6 months, have no known history of treatment failure, and are infected with HIV-1 with no known substitutions associated with resistance to dolutegravir or rilpivirine.

Used alone as a complete regimen for treatment of HIV-1 infection in these antiretroviral-experienced adults; manufacturer states concomitant use with other antiretrovirals not recommended.